Seeley & Sandoval Lab

Bariatric Surgery | Metabolism | Gut-Brain

Latest News: Dr. Sandoval accepted a new position as Professor of Pediatrics at the University of Colorado Anschutz Medical Campus. Congratulations Darleen!


The Randy Seeley and Darleen Sandoval laboratories are located in shared space at the University of Michigan Ann Arbor.

The Seeley Laboratory is interested in:

  • Identifying the molecular mechanisms underpinning the potent effects of bariatric surgery on weight and metabolism

  • Studying the actions of various peripheral hormones in the CNS that serve to regulate food intake, body weight, and the regulation of circulating fuels

  • Developing novel surgical strategies in the treatment of metabolic disease

The Sandoval Laboratory is interested in:

  • The role of intestinal vs. pancreatic sources of GLP-1 on glucose homeostasis

  • Weight loss-independent metabolic responses to bariatric surgery

  • GLP-1 neurophysiology